Contract Development
and Manufacturing

Key technologies & expertise

Polpharma API CDMO is experienced in developing and manufacturing processes using a variety of chemical reactions and conditions, including cryogenic, high pressure, strong bases reactions, API micronization, injectable grade APIs.

  • Amidation

  • Alcylation

  • Acetylation

  • Bromination

  • Chlorination

  • Chlorosulphonation

  • Cyclization

  • Coupling

  • Carboxylation

  • Dehydrogenation

  • Lithiation (with BuLi)

  • Esterefication

  • Friedl- Craft's alcylation

  • Grignard's reaction

  • Hydrogenation

  • Methylation

  • Metho-/ Ethoxylation

  • Oxidation/ Reduction

  • Phosegenation (with triphosgene)

  • Saponification

  • Strong base reactions

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